Ibikoresho bifatika bya farumasi (APIs) bigira uruhare runini mubikorwa bya farumasi kandi nibyo shingiro ryibanze ryo gukora imiti yose.
Ingano yisoko yinganda zimiti yubuyapani iza kumwanya wa kabiri muri Aziya.Hamwe no kwiyongera kwa R&D mu nganda zimiti nizindi mpamvu, biteganijwe ko isoko ry’Abayapani APIs rizazamuka ku gipimo kiri hejuru ya 7% kugeza 8% muri 2025. Muri bo, ibigo by’imiti byagize uruhare runini birimo Imiti yizuba, Teva, Novartis International AG, Piramal Enterprises, na Aurobindo.
Iterambere ry’inganda rusange z’ibiyobyabwenge n’Ubuyapani naryo rihura n’inzitizi yo gutanga ibikoresho byigenga bidahagije.Hafi ya 50% y’ibicuruzwa biva mu gihugu biva mu gihugu cya API bikoreshwa mu gukora imiti rusange, kandi abatanga ibicuruzwa mpuzamahanga mpuzamahanga baturuka mu bihugu bya Aziya n’Uburayi nku Buhinde, Ubushinwa, Koreya yepfo, Ubutaliyani, Espagne, Hongiriya n’Ubudage.Kugirango ugabanye gushingira kuri API zitumizwa mu mahanga, Ubuyapani bwibanda ku kuba APIs.
Sumitomo Pharmaceuticals, isosiyete ya mbere mu Buyapani yakoze imiti y’imiti ikoresheje ikoranabuhanga rya kijyambere rya synthesis, irateganya kubaka imiti mishya ya molekile ntoya APIs n’uruganda ruhuza umujyi wa Oita, Perefegitura ya Oita.Intego nyamukuru yuwo mushinga ni ukongera ubushobozi bw’isosiyete ya API ubushobozi bwo gukora kugira ngo ishobore gukenera kwiyongera kwa APIs n’abahuza.
Biteganijwe ko uruganda rushya ruzatangira gukoreshwa muri Nzeri 2024. Ishami ry’iterambere ry’inganda n’inganda (CDMO) rikoresha ikoranabuhanga ridasanzwe mu gukora no gutanga molekile ntoya APIs n’abahuza n’amasosiyete akora, kandi ikanagurisha ibicuruzwa byo hanze.Bitewe cyane n’imishinga mishya iteza imbere imiti, isoko rya farumasi ya CDMO ku isi ryakomeje kwiyongera.Bigereranijwe ko agaciro k’ubucuruzi ku isi muri iki gihe k’imiti ya CDMO kangana na miliyari 81 z’amadolari y’Amerika, ahwanye na tiriyari 10 yen.
Ashingiye kuri sisitemu nziza yo kwizeza ubuziranenge hamwe n’inyungu zo gucunga amasoko ku isi, Sumitomo Pharmaceuticals yaguye buhoro buhoro ubucuruzi bwa CDMO mu myaka yashize kandi ishyiraho umwanya wambere mu Buyapani.Ibihingwa byayo muri Gifu na Okayama bifite ubushobozi buke bwo gukora.Ubushobozi bukomeye bwo gukora APIs nabahuza basabwa kumiti ivura molekile.Uruganda rukora imiti y’imiti mu Buyapani Bushu Corporation rwagiranye amasezerano y’ubufatanye n’isosiyete ikora imiti ya Suzuken muri Mata 2021 kugira ngo itange inkunga nshya yo guteza imbere ibicuruzwa ku masosiyete y’imiti y’imyuga yifuza kwinjira ku isoko ry’Ubuyapani.Bushu yizera ko azakora amasezerano y’ubufatanye mu bicuruzwa bituruka mu gihugu mu buryo butaziguye, binyuze ku bufatanye n’amasosiyete yombi y’imiti, kugira ngo atange serivisi imwe y’imicungire y’ibisabwa ku miti idasanzwe, harimo no kuzamura abafite uburenganzira / abajyanama b’ibiyobyabwenge, gutumiza mu mahanga, gusuzuma isoko, Umusaruro no gutanga, ushinzwe kubika no gutwara abantu, gusuzuma kuzamura no gufasha abarwayi nizindi serivisi.
Muri icyo gihe, Pharmaceuticals ya Bushu irashobora kugeza imiti ku barwayi mu nzira zose ikoresheje uburyo bwihariye bwo gukurikirana imiti mikorobe ikonje (Cubixx) yakozwe na Suzuken Co., Ltd. Byongeye kandi, uruganda rukora imiti rwa Astellas mu Buyapani rwatangaje ko nk'uko gahunda ya gatatu yo kwagura umusaruro, ishingiro rya API ryo gukora imiti ikora neza yashinzwe i Toyama, mu Buyapani muri Mutarama 2020 izakoreshwa mu gukora umwimerere wa tacrolimus hydrat API ya Astellas Prograf.
Tacrolimus ni umuti urinda kandi uvura kwanga ingingo ku barwayi bakuze n’abana bakiriye umwijima, impyiko, umutima (hamwe n’ibihaha bishya bya FDA mu 2021).
Igihe cyo kohereza: Jun-03-2019
